Maternal and Perinatal Outcome Among Pregnant Women with Thrombocytopenia Attending Ibrahim Malik Teaching Hospital- Sudan

Gynecology and Womens Health

Thrombocytopenia is encountered in 7-8% of all pregnancies. Thrombocytopenia is second to anemia as the most common hematological abnormality during pregnancy [1- 2]. Thrombocytopenia is defined as a platelet count below 150 x109/L, caused by accelerated platelet destruction or decreased production. It is classified as mild with a platelet count of 100–150x 109/L, moderate at 50–100 x109/L, and severe with less than 50x 109/L [3-4]. In normal pregnancies 7.6% of women present with mild thrombocytopenia and 65% of them will not be associated with any pathology [5]. The most causes of thrombocytopenia during pregnancy were gestational thrombocytopenia about 8% of all pregnancies and accounts for more than 75% of cases of thrombocytopenia in pregnancy [3-5]. Platelet counts normalize within 2-12 weeks following delivery. All women with gestational thrombocytopenia had normal platelet counts by the seventh postpartum day [5]. No pathological abnormality for the mother or fetus was noted in gestational thrombocytopenia. Preeclampsia and HELLP syndrome are the second most frequent cause of thrombocytopenia in late second and third trimester, accounting for 21% of cases of thrombocytopenia at the time of delivery.

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